Regenerating Baby Fat to Fight Adult Fat
Prof. Dr. Mohamed Elhashemy
April 09, 2009
Three new studies appearing recently in the New England Journal of Medicine "NEJM" show that most adults have - unexpectedly - some active deposits of a calorie-burning type of fat known as Brown Adipose Tissue "BAT".
The first research was done by Sven Enerback, University of Goteborg in Sweden.
The second research was done by Francesco S. Celi, a metabolism researcher at the National Institutes of Health.
The third research was led by Dr Aaron Cypess of the Joslin Diabetes Center in Boston, Massachusetts.
The summary of these three researches entails that scientists found that adult humans - against old believes - had brown adipose tissue, also that slim adults had more of it than fatter ones.
These latest three studies show that brown fat may not disappear in adults and that little collections of brown fat may account for why some people are protected from obesity and diabetes 2 while others are not.
The discovery of persistence of this brown fat in adults may suggest a potential new strategy to fight obesity. Accordingly, the day may come when it will be possible to stimulate brown fat growth to treat obesity and type 2-diabetes.
It has long been known that people significantly differ in their tendency to gain weight and to develop diabetes.
There are two types of body fat: white and brown. White fat (WAT), the more familiar form of fat that accumulates in the abdomen, thighs, buttocks and under the skin, since it stores energy, it is considered more harmful than brown fat (BAT) which burns energy and generates heat. BAT is mostly concentrated in the lower part of the neck and the upper part of thorax especially at the inter-scapular region in humans especially infants.
When people eat more calories than they need, their bodies make triglycerides and store them in white fat cells; so it is considered as sacs of stored triglycerides.
In contrast to WAT, Brown Adipose Tissue is rich in mitochondria, the calorie burning "batteries" inside each cell that supply the human cells with energy. Mitochondria are full of iron-rich proteins which give brown fat cells their characteristic color.
Regeneration of BAT to fight WAT remains a challenge to many scientists who are interested in managing obesity. Among the theories postulated to induce this regeneration are:
1. Turning on a trigger protein BMP-7, known to promote the development of brown fat, this protein could encourage myoblast cells that normally produce muscle cells to produce brown instead of white fat cells. This theory has been advanced by Prof. Dr. Ronald Kahn.
2. Transplant brown fat cells into a person who is obese to help their bodies to burn more calories.
3. Elhashemy´s Triple Boost, which aims at activation and multiplication of the existing BAT in the adult human body through:
I. Potent anti-oxidants
In my opinion BAT volume is reduced in adults due to the damage resulting from exposure to pollutants, and this - also in my opinion - may be the cause why researchers found that males have lower percentage of BAT (due to their higher exposure to pollution).
I usually advise my patients to use blueberry, which is one of the richest foods in anthocyanins & pterostilbene. Small volumes of blueberry (Luqaimat in Arabic language) when taken frequently (up to 7 successive times within seven hours in each day) may result in immersing BAT in a serum of highly concentrated potent anti-oxidant.
This means that when we eat potent anti-oxidant (blueberry) we detoxicate our BAT resulting in its regeneration and activation.
II. Inter-scapular muscle exercises (using dumbbells) daily:
In my opinion this will increase blood supply to inter-scapular region, hence activating BAT aggregated in that area.
III. Inter-scapular ice bags several times per day:
In my opinion this will activate bat cells, which is well known to respond to positively to very low temperature.
This triple boost together with activating Elhashemy´s Stomach Satiety Spot "ESSS" is a great scientific diet plan formula that helped my obese patients to achieve outstanding weight loss results.
The first research was done by Sven Enerback, University of Goteborg in Sweden.
The second research was done by Francesco S. Celi, a metabolism researcher at the National Institutes of Health.
The third research was led by Dr Aaron Cypess of the Joslin Diabetes Center in Boston, Massachusetts.
The summary of these three researches entails that scientists found that adult humans - against old believes - had brown adipose tissue, also that slim adults had more of it than fatter ones.
These latest three studies show that brown fat may not disappear in adults and that little collections of brown fat may account for why some people are protected from obesity and diabetes 2 while others are not.
The discovery of persistence of this brown fat in adults may suggest a potential new strategy to fight obesity. Accordingly, the day may come when it will be possible to stimulate brown fat growth to treat obesity and type 2-diabetes.
It has long been known that people significantly differ in their tendency to gain weight and to develop diabetes.
There are two types of body fat: white and brown. White fat (WAT), the more familiar form of fat that accumulates in the abdomen, thighs, buttocks and under the skin, since it stores energy, it is considered more harmful than brown fat (BAT) which burns energy and generates heat. BAT is mostly concentrated in the lower part of the neck and the upper part of thorax especially at the inter-scapular region in humans especially infants.
When people eat more calories than they need, their bodies make triglycerides and store them in white fat cells; so it is considered as sacs of stored triglycerides.
In contrast to WAT, Brown Adipose Tissue is rich in mitochondria, the calorie burning "batteries" inside each cell that supply the human cells with energy. Mitochondria are full of iron-rich proteins which give brown fat cells their characteristic color.
Regeneration of BAT to fight WAT remains a challenge to many scientists who are interested in managing obesity. Among the theories postulated to induce this regeneration are:
1. Turning on a trigger protein BMP-7, known to promote the development of brown fat, this protein could encourage myoblast cells that normally produce muscle cells to produce brown instead of white fat cells. This theory has been advanced by Prof. Dr. Ronald Kahn.
2. Transplant brown fat cells into a person who is obese to help their bodies to burn more calories.
3. Elhashemy´s Triple Boost, which aims at activation and multiplication of the existing BAT in the adult human body through:
I. Potent anti-oxidants
In my opinion BAT volume is reduced in adults due to the damage resulting from exposure to pollutants, and this - also in my opinion - may be the cause why researchers found that males have lower percentage of BAT (due to their higher exposure to pollution).
I usually advise my patients to use blueberry, which is one of the richest foods in anthocyanins & pterostilbene. Small volumes of blueberry (Luqaimat in Arabic language) when taken frequently (up to 7 successive times within seven hours in each day) may result in immersing BAT in a serum of highly concentrated potent anti-oxidant.
This means that when we eat potent anti-oxidant (blueberry) we detoxicate our BAT resulting in its regeneration and activation.
II. Inter-scapular muscle exercises (using dumbbells) daily:
In my opinion this will increase blood supply to inter-scapular region, hence activating BAT aggregated in that area.
III. Inter-scapular ice bags several times per day:
In my opinion this will activate bat cells, which is well known to respond to positively to very low temperature.
This triple boost together with activating Elhashemy´s Stomach Satiety Spot "ESSS" is a great scientific diet plan formula that helped my obese patients to achieve outstanding weight loss results.
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