Type 1 Diabetes Juvenile International Study, What It Is All About

Roger Guzman, M.D.
Type 1 diabetes international study received $169 million dollars to analyze results from a 10-year international study of juvenile diabetes. The analysis will find out the environmental causes of the disease. The aim is to delay, reverse or prevent this condition.

Jeffrey Krischer will lead the University of Southern Florida Health team. The National Institutes of Health awarded this 10-year grant which is the largest in the history of USF. Clinical sites all over the world will screen 360,000 newborns to track 8000 babies.

Eventually they will analyze over 100,000 lab tests. Stephen Klasko, MD, MBA and USF Vice president and Dean of the College of Medicine said that Dr. Krischer´s team is the center for almost all major study on the prevention of type 1 diabetes in the world.

Dr. Klasko has unlocked auto-immune diseases. Among these, the most serious and common is juvenile diabetes. The team will look for reasons why some kids get juvenile diabetes. They will also try to find out why the number of cases has doubled since the 1980´s.

The study is known as TEDDY which is an acronym for The Environmental Determinants of Diabetes in the Young. Families with newborns will be enlisted over five years. Then they will be followed up until the newborns are 15 years old. They know that some have more risk of diabetes, genetically, but this only accounts for the 10% of those who develop the disease.

Just recently, I read that they were granted an additional $10 million dollars for this TEDDY Study. There was another physician named Dr. She who reported that genetics may not be the only cause as the increase in the number of cases does not seem to support this because genetics do not go that fast. This led me to dig deeper and this is what I found.

The purpose of the study is to look at the causes of type 1 diabetes in children. It is a known fact that this happens when the beta cells of the pancreas that manufacture insulin are destroyed by the immune cells. This action makes the beta cells unable to do its job of producing insulin.


The trouble is the body needs the insulin to keep the blood sugar normal. The lack of insulin makes the blood sugar level high making the person sick as a result. That is why children who have type 1 diabetes need to take insulin and monitor their blood sugar level in order to stay healthy and alive.

The researchers will identify the dietary factors, infectious cause and other agents in the environment plus the psychosocial issues that set off the condition among the children who are genetically at high risk to develop it and what among those agents protect the same type of children against the disease.

The children who get diabetes have genes that make them at risk to develop diabetes. Herein lies the problem. Not all children with these genes develop this condition so the researchers believe there are other things that cause some children to develop it. This is what they are trying to find out in this study: what causes type 1 diabetes.

Please visit these sites for more diabetes help:

Type 1 Diabetes

Type 1 Diabetes Cause

Copyright © December 29, 2008 Roger Guzman, M.D. (Type 1 Diabetes Juvenile International Study Awarded $169 Million Dollars) All Rights Reserved. You may copy and publish this article as long as the text, the author's name, the active links and this notice remain the same.
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Roger Guzman, M.D.

Brief Biography: Dr. Guzman worked for the Atlantic Health Corporation and was consultant to St. Joseph's Hospital, Sussex Mental Health Clinic, and St. Stephen Mental Health Clinic for many years. He was Director of Forensic Psychiatry at Centracare for ten years and published numerous articles in the Journal of the American College of Forensic Psychiatry and other medical magazines.

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